Methoxphenidine (MXP)



IUPAC-Name:  (±)-1-[1-(2-methoxyphenyl)-2-phenylethyl]piperidine

Other Names:  Methoxphenidine, Methoxydiphenidine, 2-MeO-Diphenidine, MXP

Chemical Class:  Piperidine

CAS #:  127529-46-8

Formula:  C20H25NO

Molar Mass:  295.42 g/mol


Methoxphenidine, or 2-MeO-Diphenidine, is a synthetic compound of the diarylethylamine class. Methoxphenidine’s chemical structure contains a substituted phenethylamine skeleton with an additional phenyl ring bound to Rα. The terminal amino group of the phenethylamine chain is incorporated into a piperidine ring. Hence, methoxphenidine belongs to the piperidine dissociative class of compounds.

Structurally similar to Ketamine, Methoxphenidine is an antagonist of the NMDA receptor, and suitable as a substitute for methoxetamine (MXE)

Methoxphenidine is a structural analog of diphenidine, featuring a methoxy group at the two position of a phenyl group.

Methoxphenidine (MXP) or 1-[1-(2-methoxyphenyl)-2-phenylethyl]piperidine is a hallucinogenic dissociative compound of the piperidine chemical class. It has similar effects to that of the arylcyclohexylamine and morphinan classes of dissociatives. It induces a state referred to as “dissociative anesthesia” and is used as a recreational drug.

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